When tabbing out of a DotA 2 game on Debian Stable, occasionally, the sound breaks. Requiring a restart and reconnect.

I've forever been using the Video > advanced settings with Desktop-friendly Fullscreen and the additional Desktop-friendly Fullscreen minimizes on focus loss. When I got a new monitor it switched back to the default Use my monitor's current resolution.

And with that, the issues were gone. So, if you have similar sound issues, make sure you don't use the advanced video settings.